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DeCS
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Descriptor English:
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Janus Kinases
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Descriptor Spanish:
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Quinasas Janus
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Descriptor Portuguese:
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Janus Quinases
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Synonyms English:
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JAK Kinases
Kinases, JAK
Kinases, Janus
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Tree Number:
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D08.811.913.696.620.682.725.124
D12.776.476.393
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Definition English:
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A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains. |
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See Related English:
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src Homology Domains
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History Note English:
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2007
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Allowable Qualifiers English:
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Record Number:
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52252
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Unique Identifier:
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D053612
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Occurrence in VHL:
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Similar:
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DeCS
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